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  • Title: [Determination of serum neuron-specific enolase in bronchial tumors of neuroendocrine origin].
    Author: Rapellino M, Pecchio F, Cunazza M, Baldi S, Adamo MR, Casadio C, Faga C, Baldi C, Oliaro A, Albertino B.
    Journal: Minerva Med; 1988 Dec; 79(12):1051-2. PubMed ID: 2850512.
    Abstract:
    Neurone-specific enolase, a serum marker of neuroendocrine tumours has been determined in small-cell anaplastic bronchial carcinomas, in typical and atypical carcinoid. The marker presents good sensitivity in small-cell tumours and in atypical carcinoids, while blood levels are within normal limits in cases of typical carcinoid. The low serum levels of neurone-specific enolase found in typical carcinoid suggest a failure of the enzyme to express itself in the circulation owing to the poor or lack of cellular necrosis.
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