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  • Title: [Effects of angiotensin-converting enzyme inhibitors in hypertension].
    Author: Rahn KH.
    Journal: Z Kardiol; 1988; 77 Suppl 3():69-71. PubMed ID: 2850690.
    Abstract:
    Angiotensin-converting-enzyme(ACE)-inhibitors reduce the formation of angiotensin II from angiotensin I. These drugs cause a substantial fall in blood pressure in patients with various forms of hypertension. In particular, the combination of ACE-inhibitors with diuretics and, if necessary, additionally beta-blockers or calcium antagonists, has also been shown to be effective in patients with otherwise resistant hypertension. ACE-inhibitors may cause serious side-effects, but, on the other hand, these drugs often have a favourable effect on the quality of life during long-term treatment.
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