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  • Title: In vitro expression of the alpha and beta subunits of the Na,K-ATPase.
    Author: Gilmore-Hebert M, Mercer RW, Schneider JW, Benz EJ.
    Journal: Prog Clin Biol Res; 1988; 268B():71-6. PubMed ID: 2851832.
    Abstract:
    Our analysis of the cloned alpha 3 protein strongly suggests that this c-DNA represents a bona fide Na+,K+ ATPase isoform. Its similarity to alpha + may have made its detection in tissues by gel migration or immunoreactivity difficult. Expression of an enzymatically active alpha 3 beta Na+K+ATPase either in a completely in vitro system or in a heterologous tissue culture system will clearly establish the biochemical properties of this isoform. Development of alpha 3 specific immunochemical probes will allow a proper assessment of its in vivo expression.
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