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  • Title: [Evaluation of the functional state of the leprous macrophages].
    Author: Maslov AK, Iushchenko AA.
    Journal: Arkh Patol; 1988; 50(11):51-4. PubMed ID: 2852935.
    Abstract:
    Cytochrome oxidase (CCO), peroxidase, succinic dehydrogenase (SDG) and NADH-diaphorase were studied electron-cytochemically in leprous macrophages (LM) of granulomas of patients suffering from lepromatous leprosy. The LM peroxidase activity and location differed, this affecting the completeness of M. leprae phagocytosis. High CCO activity in LM cytoplasm was not a factor essentially influencing M. leprae disintegration. SDG and NADH-diaphorase, locating predominantly in membraneous structures of M. leprae, show low activity in LM cytoplasm.
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