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  • Title: Expression of oncogenes in human hepatoma cell lines.
    Author: Ting LP, Jeng KS, Chou CK, Su TS, Hu CP, Wong FH, Chang HK, Chang CM.
    Journal: Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi; 1988 Aug; 21(3):141-50. PubMed ID: 2854043.
    Abstract:
    The expression of 20 known cellular proto-oncogenes in human well-differentiated hepatoma cell line Hep3B and poorly-differentiated hepatoma cell line HA22T/VGH was studied by Northern blot hybridization. Among the cellular proto-oncogenes examined, both cell lines express protein kinase genes including fps, mos and raf; PDGF B chain sis gene; GTP/GDP binding protein gene Ha-ras and nuclear protein genes including fos and myc. The expression of yes, abl, ros, src, erb-B, erb-A, fms, Ki-ras, myb, rel and bas genes was not detected in both cell lines.
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