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  • Title: The role of IL-12/23 in T cell-related chronic inflammation: implications of immunodeficiency and therapeutic blockade.
    Author: Schurich A, Raine C, Morris V, Ciurtin C.
    Journal: Rheumatology (Oxford); 2018 Feb 01; 57(2):246-254. PubMed ID: 28541488.
    Abstract:
    In this review we discuss the divergent role of two closely related cytokines, IL-12 and IL-23, in shaping immune responses. In light of current therapeutic developments using biologic agents to block these two pathways, a better understanding of the immunological function of these cytokines is pivotal.
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