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  • Title: [A clinical study of testicular tumors].
    Author: Matsuki H, Ozono S, Arai K, Saka M, Cho M, Nakagawa Y, Kaneko Y, Yoshida K, Okamoto S, Maruyama Y.
    Journal: Hinyokika Kiyo; 1988 Oct; 34(10):1757-65. PubMed ID: 2854363.
    Abstract:
    Thirty-one patients with testicular germ cell tumors were treated in our Department between January, 1979 and June, 1987. Of the 31 patients, 17 (54.8%) had seminoma and 14 (45.2%) had non-seminomatous germ cell tumor (NSGCT) histopathologically. Clinical stage of seminoma was stage I in 13 patients (76.5%) and stage II in 4 patients (23.5%). Clinical stage of NSGCT was stage I in 8 patients (57.2%), stage II in 1 patient (7.1%) and stage III in 5 patients (35.7%). The patients with stage II seminoma underwent high inguinal orchiectomy, radiation therapy, retroperitoneal lymphnode dissection (RPLND) and chemotherapy, and those with stage II and III NSGCT underwent high inguinal orchiectomy and chemotherapy. All patients with stage II seminoma are alive with no evidence of disease. Three patients with stage II and III NSGCT are alive with no evidence of disease, but 3 patients died of the disease. Survival of patients with stage I and II seminoma at 5 years was 100% Survival of stage I and II NSGCT and III NSGCT at 5 years was 100% and 40%, respectively. According to our experience, for patients with advanced seminoma, combination chemotherapy and RPLND as well as radiation therapy are effective. In addition, for patients with advanced NSCGT, adjuvant chemotherapy followed by RPLND is effective.
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