These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Aminoglycoside 3'-phosphotransferase gene: its cloning, characteristics and use as a molecular probe].
    Author: Vakulenko SB, Entina EG, Fomina IP, Navashin SM.
    Journal: Antibiot Khimioter; 1988 Dec; 33(12):913-7. PubMed ID: 2854460.
    Abstract:
    Aminoglycoside resistance genes were cloned from transconjugates of aminoglycoside resistant clinical strains of gramnegative bacteria. The resistance determinant cloned from the strains of E. coli transferred kanamycin, monomycin and neomycin resistance to laboratory strains. It was shown that the cloned resistance gene encoded the type I 3'-aminoglycoside phosphotransferase. The results of spot and blot hybridization of the gramnegative bacteria clinical strains with the Bam HI-Pst I fragment of the cloned resistance determinant were indicative of wide-spread distribution of the APH 3' (I) and closely related genes in clinical microbial populations.
    [Abstract] [Full Text] [Related] [New Search]