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  • Title: Primitive neuroectodermal tumor presenting as a delayed sequela to cranial irradiation and intrathecal methotrexate.
    Author: Barasch ES, Altieri D, Decker RE, Ahmed S, Lin J.
    Journal: Pediatr Neurol; 1988; 4(6):375-8. PubMed ID: 2854471.
    Abstract:
    A patient developed a primitive neuroectodermal tumor (PNET) many years after therapeutic cerebral radiation and methotrexate treatment for leukemia. The differential radiologic and histologic diagnoses, as well as the possible co-oncogenic effects of radiation and methotrexate, are evaluated.
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