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  • Title: Circulation of blaKPC-3-Carrying IncX3 Plasmids among Citrobacter freundii Isolates in an Italian Hospital.
    Author: Venditti C, Fortini D, Villa L, Vulcano A, D'Arezzo S, Capone A, Petrosillo N, Nisii C, Carattoli A, Di Caro A.
    Journal: Antimicrob Agents Chemother; 2017 Aug; 61(8):. PubMed ID: 28559268.
    Abstract:
    Colonizations due to carbapenem-resistant Enterobacteriaceae (CRE) are a source of antimicrobial resistance transmission in health care settings. Eleven Citrobacter freundii strains producing KPC-3 carbapenemase were isolated from rectal swabs during a 3-year surveillance program. blaKPC-3-carrying plasmids were found to belong to the IncX3 group in 9 of the 11 strains, and complete nucleotide sequences were obtained for 2 of them. Our results highlight the possible role of C. freundii as reservoir of resistance genes.
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