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  • Title: Comparison of the effects of calcium alpha-glycerophosphate and Ca2+ on prostaglandin synthesis in rabbit kidney medulla slices.
    Author: Fujita T, Kasatani H, Suzuki K, Fujimoto Y.
    Journal: Comp Biochem Physiol C Comp Pharmacol Toxicol; 1985; 80(1):141-3. PubMed ID: 2858334.
    Abstract:
    The stimulatory effects of calcium alpha-glycerophosphate (CaG) and Ca2+ on the generation of medullary prostaglandin E2 have been compared. CaG (4mM) was significantly more effective than Ca2+ (4 mM) as a stimulus for prostaglandin E2 release. This effect of CaG was most pronounced in the presence of exogenous phospholipase A2 (0.1 unit/ml). These results suggest that CaG has a more powerful stimulatory effect on prostaglandin E2 formation than Ca2+ because of its high affinity for phospholipase A2.
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