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  • Title: New Benzenoid Derivatives and Other Constituents from Lawsonia inermis with Inhibitory Activity against NO Production.
    Author: Yang CS, Chen JJ, Huang HC, Huang GJ, Wang SY, Sung PJ, Cheng MJ, Wu MD, Kuo YH.
    Journal: Molecules; 2017 Jun 05; 22(6):. PubMed ID: 28587259.
    Abstract:
    Three new benzenoid derivatives, lawsoinermone (1), inermidioic acid (2), and inermic acid (3) have been isolated from the aerial part of Lawsonia inermis, together with 11 known compounds (4-14). The structures of three new compounds were determined through spectroscopic and MS analyses. Compounds 1, 4-6, 13 and 14 were evaluated for inhibition of nitric oxide production in LPS-stimulated product of nitrite in RAW 264.7 cells with IC50 values of 6.12, 16.43, 18.98, 9.30, 9.30 and 14.90 μg/mL, respectively.
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