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  • Title: Three new flavanoids from artificially induced dragon's blood of Dracaena cambodiana.
    Author: Li FX, Wang H, Gai CJ, Chen HQ, Li W, Mei WL, Dai HF.
    Journal: J Asian Nat Prod Res; 2018 Jan; 20(1):55-61. PubMed ID: 28597686.
    Abstract:
    Three new flavanoids, (2R)-7,4'-dihydroxy-8-methylflavan (1), (2R)-7,4'-dihydroxy-6-methylflavan (2), and (3R)-7,3',4'-trihydroxyhomoisoflavan (3), together with seven known compounds (4-10), were isolated from artificially induced dragon's blood of Dracaena cambodiana, and their structures were determined based on HR-ESI-MS and extensive spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 2 exhibited weak cytotoxicity against BEL-7402 cells line with the IC50 value of 39.2 μM. In addition, compound 3 showed significant acetylcholinesterase (AChE) inhibitory activity.
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