These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Calcifying epithelial odontogenic tumor: An updated analysis of 339 cases reported in the literature.
    Author: Chrcanovic BR, Gomez RS.
    Journal: J Craniomaxillofac Surg; 2017 Aug; 45(8):1117-1123. PubMed ID: 28601296.
    Abstract:
    PURPOSE: The aim of this study was to integrate the available data published on calcifying epithelial odontogenic tumors (CEOT) into a comprehensive analysis of its clinical and radiologic features. MATERIALS AND METHODS: An electronic search was undertaken in May 2016. Eligibility criteria were publications having enough clinical, radiological and/or histological information to confirm definite diagnosis. RESULTS: A total of 362 lesions were found, 339 with enough information were analyzed. Variants clear cells (n = 33) and Langerhans cells (n = 10) were rarely described in the literature, as well as lesions with malignant transformation (n = 8). Central lesions (n = 264) were more prevalent than their peripheral counterparts (n = 24). A higher prevalence characterized the mandible, posterior region, and third and fourth decades. About 40% of the peripheral lesions showed signs of underlying bone erosion, and about half of the central ones showed signs of cortical bone perforation. Recurrence was found in all lesions (12.6%), peripheral lesions (18.8%), central lesions (11.6%), clear cell (10.7%), Langerhans cell (0%), and those with malignant transformation (42.9%). Excision or curettage was associated with the highest recurrence rate. None of the variables showed a statistically significant influence on the recurrence rate. CONCLUSIONS: The possible locally aggressive behavior of the lesions recommends a less conservative management than simple curettage. The clear cell variant shows similar demographic data and biological behavior compared to the non-variant lesions, suggesting that the presence of clear cells does not have an important clinical significance.
    [Abstract] [Full Text] [Related] [New Search]