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  • Title: Age-related changes in monoamine oxidase and semicarbazide-sensitive amine oxidase activities of rat aorta.
    Author: Cao Danh H, Strolin Benedetti M, Dostert P, Mousset A.
    Journal: J Pharm Pharmacol; 1985 May; 37(5):354-7. PubMed ID: 2862248.
    Abstract:
    Aorta MAO-A and SSAO activities were measured on young (3 months) and old (23-26 months) rats. A significant decrease (30-40%) in SSAO activity was found with benzylamine as substrate and the decrease was due to a reduction in Vmax. No significant changes in MAO-A activity were found in the aorta of old rats. beta-PEA is oxidized mainly by SSAO in rat aorta. However, the significance of this is unclear since the physiological role of that enzyme remains unknown.
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