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  • Title: Inhibition of quantal transmitter release by the polycationic ligand cationized ferritin.
    Author: Publicover SJ.
    Journal: Exp Brain Res; 1985; 59(3):629-32. PubMed ID: 2863166.
    Abstract:
    Cationized ferritin (200 micrograms ml-1) causes a reduction in both spontaneous and evoked transmitter release at the frog neuromuscular junction. The reduction in EPP amplitude probably reflects reduced Ca2+ -influx since full recovery can be achieved by elevation of [Ca2+]o. The effect on MEPP frequency is independent of [Ca2+]o and may well reflect a direct effect on exocytosis.
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