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  • Title: [The affinity of aromatic fluoride derivatives of phenothiazine neuroleptics to spiroperidol binding sites of dopamine receptors by the radioligand technic in vitro].
    Author: Oelssner W, Peinhardt G, Büge A.
    Journal: Pharmazie; 1985 May; 40(5):341-2. PubMed ID: 2863832.
    Abstract:
    By introduction of fluorine into the position 7 of butaperazine, chlorpromazine, methoxypromazine, perphenazine, prochlorperazine or into the position 3 of promazine derivatives are obtained with higher affinities for the 3H-spiroperidol binding site of the dopamine receptor compared with the corresponding substances free of fluorine.
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