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  • Title: [Enzyme diagnostic criteria of alcoholism].
    Author: Piatnitskaia IN, Chernobrovkina TV, Goriushkin II.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1985; 85(7):1051-3. PubMed ID: 2863908.
    Abstract:
    Activity of gamma-glutamyltransferase (GGT), aspartate aminotransferase (AsAT) and alanine aminotransferase was determined repeatedly for 5-10 days in the blood serum of patients with Stage I-II alcoholism (n-63) and healthy subjects (n-31). Alcoholism was associated with an elevated activity of GGT and AsAT and its dynamic fluctuations in both directions due to a change in the status of the test subject. It is stated that alcoholism in the considered enzymological manifestations is a pathogenetically unstable state. The authors recommend including the measurement of these enzymes into the complex of measures for alcoholism diagnosis.
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