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  • Title: A new hemoglobin variant, Hb Mito [beta 144(HC 1) Lys----Glu], with increased oxygen affinity.
    Author: Harano K, Harano T, Ueda S, Ohkushi T, Imai K.
    Journal: FEBS Lett; 1985 Nov 11; 192(1):75-8. PubMed ID: 2865170.
    Abstract:
    A new abnormal hemoglobin, Hb Mito [beta 144(HC 1) Lys----Glu], with an amino acid substitution in the 2,3-DPG pocket, was discovered in a Japanese female. This hemoglobin showed increased oxygen affinity, and decreased organic phosphate and Bohr effects, while the Hill constant n was normal.
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