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  • Title: Homovanillic acid in caudate and pre-frontal cortex following acute and chronic neuroleptic administration.
    Author: Bowers MB, Hoffman FJ.
    Journal: Psychopharmacology (Berl); 1986; 88(1):63-5. PubMed ID: 2868484.
    Abstract:
    Homovanillic acid (HVA) was measured in rat caudate and pre-frontal cortex after single and repeated doses of several types of neuroleptic drugs. Twice daily administration of low or high doses of haloperidol, fluphenazine, or (-) sulpiride resulted in greater tolerance to the initial HVA increase in caudate compared to prefrontal cortex.
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