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  • Title: Urinary albumin, immunoglobulin G and Beta-microglobulin in the diagnosis of diabetes in the elderly.
    Author: Li J, Zhang LM, Huang X.
    Journal: J Biol Regul Homeost Agents; 2017; 31(2):395-398. PubMed ID: 28685543.
    Abstract:
    Diabetes shows no obvious clinical symptoms in the early stage, which makes it difficult to be detected; however, as a common and frequently occurring disease, its morbidity increases with the improvement in the standard of living. Therefore, early detection, diagnosis and treatment of diabetes are of great importance. This study investigated the application values of urinary albumin (Alb), immunoglobulin G (IgG) and Beta-microglobulin (β2mG) in the diagnosis of diabetes. Seventy-four elderly patients with confirmed diabetes who were admitted to the Central Hospital of Zibo from May 2014 to May 2015 were taken as an observation group, and fifty normal healthy people were taken as a control group. Levels and positive detection rates of Alb, IgG and β2mG in the two groups were compared. The results showed that the levels of Alb, IgG and β2mG of the observation group were higher than those of the control group, and the positive detection rates of Alb, IgG and β2mG were 74.3%, 62.2% and 67.6%, respectively, which were higher than 6%, 16% and 12% in the control group; the differences were all statistically significant (P less than 0.05). The difference of the content of Alb, IgG and β2mG between patients with different disease courses was statistically significant (P less than 0.05). Therefore, Alb, IgG and β2mG levels are closely related to severity of diabetes, which provides a medical reference to the diagnosis and examination of diabetes and has important clinical values.
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