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  • Title: Cyclophosphamide and cisplatinum combination chemotherapy for the treatment of epithelial ovarian carcinoma.
    Author: Hahn K, Magrina JF, Masterson BJ.
    Journal: Int J Gynaecol Obstet; 1985 Dec; 23(6):509-13. PubMed ID: 2868947.
    Abstract:
    A review of 18 patients with Stage III epithelial ovarian carcinoma treated by surgery and followed by cyclophosphamide and cisplatinum combination chemotherapy is presented. At the end of 12 months from the initiation of chemotherapy, 88.9% of the patients were alive and 77.8% remained free of tumor progression. At the end of 2 years 77.8% of the patients were alive and 44.4% of the patients were free of tumor progression. The combination of cyclophosphamide and cisplatinum has low toxicity, a simple pattern of administration, and has provided satisfactory results.
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