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  • Title: Biofilms Formed by Isolates from Recurrent Vulvovaginal Candidiasis Patients Are Heterogeneous and Insensitive to Fluconazole.
    Author: Sherry L, Kean R, McKloud E, O'Donnell LE, Metcalfe R, Jones BL, Ramage G.
    Journal: Antimicrob Agents Chemother; 2017 Sep; 61(9):. PubMed ID: 28696240.
    Abstract:
    Vulvovaginal candidiasis (VVC) is a global health problem affecting ∼75% of women at least once in their lifetime. Here we examined the epidemiology of VVC in a patient cohort to identify the causative organisms associated with VVC. Biofilm-forming capacity and antifungal sensitivity profiles were also assessed. We report a shifting prevalence of Candida species with heterogeneous biofilm-forming capacity, which is associated with altered antifungal drug sensitivity.
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