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  • Title: Effects of vecuronium bromide on intracranial pressure and cerebral perfusion pressure. A preliminary report.
    Author: Rosa G, Sanfilippo M, Vilardi V, Orfei P, Gasparetto A.
    Journal: Br J Anaesth; 1986 Apr; 58(4):437-40. PubMed ID: 2869774.
    Abstract:
    The effects of vecuronium 0.1 mg kg-1 on intracranial pressure, heart rate and arterial pressure were evaluated in 20 anaesthetized patients with intracranial tumours undergoing neurosurgery. Apart from a slight decrease in intracranial pressure (-4.9%; ns) which was most probably the result of a concomitant decrease (-14.9%) in central venous pressure, vecuronium 0.1 mg kg-1 was without effect on either cerebral or systemic haemodynamics.
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