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  • Title: [Effectiveness and tolerance of metipranolol--results of a multi-center long-term study in Switzerland].
    Author: Müller O, Knobel HR.
    Journal: Klin Monbl Augenheilkd; 1986 Jan; 188(1):62-3. PubMed ID: 2870216.
    Abstract:
    The results of this continuing multicenter study revealed a good efficacy and tolerance of Metipranolol used in patients with ocular hypertension and chronic open-angle glaucoma. After 4 weeks' treatment a reduction in average intraocular pressure of 5.6 mmHg could be observed. This favorable effect on pressure values could be confirmed during long-term treatment up to 16 weeks (average reduction in intraocular pressure of 5.9 mmHg equal to 25%). More than 90% of patients treated with 0.1% Metipranolol showed very good or good tolerance. In conclusion, it can be established that 0.1% Metipranolol has also confirmed its value in daily practice and offers an interesting possibility for low-dosage beta-blocker therapy.
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