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  • Title: [Effect of immunomodulators on resistance to gas gangrene. The enhanced resistance of white mice to perfringens toxin type A as affected by prodigiozan].
    Author: Konikova RE, Stepanov AV, Sviridov LP.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1986 Feb; (2):81-4. PubMed ID: 2870596.
    Abstract:
    Experiments on 575 noninbred white mice have revealed that the nonspecific resistance of the animals to type A C. perfringens toxin can be enhanced by the administration of Prodigiosan, a commercial immunostimulating agent. Prodigiosan, introduced in 3-4 injections (the last one made 24 hours before intoxication) has been found to enhance the resistance of the animals to the subcutaneous injection of type A C. perfringens toxin by 40-60% and to its intraperitoneal injection by 60-97%.
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