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  • Title: Sulphasalazine in the treatment of juvenile rheumatoid arthritis: a preliminary open trial.
    Author: Ozdogan H, Turunç M, Deringöl B, Yurdakul S, Yazici H.
    Journal: J Rheumatol; 1986 Feb; 13(1):124-5. PubMed ID: 2871188.
    Abstract:
    Sulphasalazine was administered to 18 patients with juvenile rheumatoid arthritis (JRA). The mean duration of therapy was 7.8 +/- 2.6 months. There was significant improvement in all clinical variables and erythrocyte sedimentation rate. Five children developed minor and transient side effects. Medication was discontinued in 3 patients: one because of leukopenia, 2 for lack of effect. These results suggest that sulphasalazine is an effective and relatively safe drug which may prove to be a useful second line agent in the management of JRA.
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