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  • Title: Evidence for HTLV-I associated with mycosis fungoides and B-cell chronic lymphocytic leukemia.
    Author: Peterman A, Jerdan M, Staal S, Bender B, Striecher H, Schüpbach J, Resnick L.
    Journal: Arch Dermatol; 1986 May; 122(5):568-71. PubMed ID: 2871815.
    Abstract:
    Human T-cell lymphotropic virus type I (HTLV-I) is a human retrovirus that can transform T-helper lymphocytes and is etiologically associated with adult T-cell lymphoma/leukemia. Mycosis fungoides represents a primary cutaneous lymphoma of helper T-cell origin, while chronic lymphocytic leukemia is generally considered to be a neoplastic B-lymphocyte disorder. Our patient had HTLV-I with coexistent mycosis fungoides and B-cell chronic lymphocytic leukemia. The concurrent lymphoid proliferations may represent HTLV-I-associated abnormalities of immunoregulation.
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