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  • Title: Mechanical properties of denervated amphibian muscle.
    Author: McDonagh MJ, Lewis DM, Wernberg-Möller S.
    Journal: Comp Biochem Physiol A Comp Physiol; 1986; 84(1):123-6. PubMed ID: 2871966.
    Abstract:
    Denervated amphibian muscle does not show the prolongation of action potential found in mammalian denervated muscle. It was, therefore, predicted that denervated amphibian muscle would not show prolongation of the mechanical twitch. The sartorius muscles in one leg of toads--Xenopus borealis--were denervated for 140-268 days. Isometric twitch time to peak, time to half relaxation and twitch/tetanus ratio were not changed following denervation, confirming our prediction. Twitch tension decreased to 68% and tetanic tension decreased to 75% of control values. The maximum velocity of unloaded shortening (muscle length/s) was also unchanged.
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