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  • Title: Sam68 Offers Selectively Aimed Modulation of Transcription in Cancer Stem Cells.
    Author: Fu K, Wan F.
    Journal: Cell Chem Biol; 2017 Jul 20; 24(7):777-779. PubMed ID: 28732196.
    Abstract:
    In this issue of Cell Chemical Biology,Benoit et al. (2017) report the selective targeting of cancer stem cells (CSCs) by the ICG-001/CWP family of molecules. Their findings reveal that Sam68 is a transcriptional modulator uniquely required for the dysregulated Wnt/β-catenin signaling in CSCs over healthy stem cells.
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