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  • Title: Mechanical Valve Thrombosis on Rivaroxaban: Are Novel Anticoagulants Really an Option?
    Author: Kumar V, Kelly S, Raizada A, Yee J, Anuwatworn A, Stys A, Stys M.
    Journal: Methodist Debakey Cardiovasc J; 2017; 13(2):73-75. PubMed ID: 28740586.
    Abstract:
    This is a case of a 54-year-old female with a history of mechanical aortic valve replacement who presented in cardiogenic shock. Her primary care provider started her on rivaroxaban for anticoagulation therapy. An urgent transesophageal echocardiogram revealed a significant gradient and thrombosis on one leaflet of the valve that was immobile. Given that she was not a surgical candidate, she underwent thrombolysis. However, she later died due to complications from the thrombotic valve. The utility of target-specific oral anticoagulants has yet to be established in clinical practice.
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