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  • Title: Amino acid sequence of the plasma membrane ATPase of Neurospora crassa: deduction from genomic and cDNA sequences.
    Author: Hager KM, Mandala SM, Davenport JW, Speicher DW, Benz EJ, Slayman CW.
    Journal: Proc Natl Acad Sci U S A; 1986 Oct; 83(20):7693-7. PubMed ID: 2876429.
    Abstract:
    The plasma membrane of Neurospora crassa contains an electrogenic H+-ATPase (EC 3.6.1.35), for which we have isolated and sequenced both genomic and cDNA clones. The ATPase gene is interrupted by four small introns (58-124 base pairs). It encodes a protein of 920 amino acids (Mr, 99,886) possessing as many as eight transmembrane segments. The Neurospora ATPase shows significant amino acid sequence homology with the Na+,K+- and Ca2+-transporting ATPases of animal cells, particularly in regions that appear to be involved in ATP binding and hydrolysis.
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