These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effects of diuretics and adrenergic-blocking agents on plasma lipids.
    Author: Rohlfing JJ, Brunzell JD.
    Journal: West J Med; 1986 Aug; 145(2):210-8. PubMed ID: 2876554.
    Abstract:
    ANTIHYPERTENSIVE MEDICATIONS CAUSE THE FOLLOWING CHANGES IN PLASMA LIPIDS AND LIPOPROTEINS: Thiazide and loop diuretics increase triglyceride, total cholesterol and low-density-lipoprotein (LDL) cholesterol levels with no change in high-density-lipoprotein (HDL) cholesterol. beta-Adrenergic antagonists increase triglyceride and decrease HDL cholesterol levels. A rise in very-low-density-lipoprotein (VLDL) cholesterol balances the decrease in HDL cholesterol, so that there is no significant change in total cholesterol. alpha-Adrenergic antagonists decrease triglyceride, increase HDL cholesterol and may decrease VLDL and LDL cholesterol. Labetalol, with both alpha- and beta-adrenergic antagonistic activity, does not affect plasma lipids in a small number of studies. The calcium channel blockers nifedipine and verapamil also have no consistent effect on lipoprotein levels in a small number of studies.
    [Abstract] [Full Text] [Related] [New Search]