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  • Title: Enzyme activity in mice with transplantable leukemia.
    Author: Sobiech KA, Madej JA, Fiszer-Maliszewska L, Mazurkiewicz M.
    Journal: Arch Immunol Ther Exp (Warsz); 1986; 34(1):35-43. PubMed ID: 2877646.
    Abstract:
    Activity of cobalt activated acylase, gamma-glutamyltransferase, leucylaminopeptidase and alanylaminopeptidase in serum and liver of mice with transplantable leukemias (L1210, L1210/ara-C, L1210/CH3-G, AKSL-4, plasmacytoma ADJ-PC-5) were determined. Adenosinotriphosphatase, 5'-nucleotidase and alkaline phosphatase were histochemically localized in lymphatic nodes and spleen. Among the investigated enzymes the rise in serum activity of cobalt activated acylase and gamma-glutamyltransferase was demonstrated. A substantial increase of leucylaminopeptidase and alanylaminopeptidase was shown in the liver. A decrease in the histochemical reactions of all the studied enzymes was observed.
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