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  • Title: Clinical Inquiry: What is the most effective treatment for scabies?
    Author: Campbell JJ, Paulson CP, Nashelsky J.
    Journal: J Fam Pract; 2017 Aug; 66(8):E11-E12. PubMed ID: 28783773.
    Abstract:
    Topical permethrin is the most effective treatment for classic scabies (strength of recommendation [SOR]: A, meta-analyses with consistent results). Topical lindane and crotamiton are inferior to permethrin but appear equivalent to each other and benzyl benzoate, sulfur, and natural synergized pyrethrins (SOR: B, limited randomized trials). Although not as effective as topical permethrin, oral ivermectin is an effective treatment compared with placebo (SOR: B, a single small randomized trial). Oral ivermectin may reduce the prevalence of scabies at one year in populations with endemic disease more than topical permethrin (SOR: B, a single randomized trial).
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