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  • Title: Subacute Toxicity Effects of Deltamethrin on Oxidative Stress Markers in Rainbow Trout.
    Author: Elia AC, Giorda F, Pacini N, Dörr AJM, Scanzio T, Prearo M.
    Journal: J Aquat Anim Health; 2017 Sep; 29(3):165-172. PubMed ID: 28792275.
    Abstract:
    Deltamethrin is a pyrethroid insecticide that is considered extremely toxic to aquatic organisms. We evaluated the effect of subacute doses (0.033, 0.1, or 0.3 mg/kg) of deltamethrin on micronucleus frequency and oxidative stress markers in Rainbow Trout Oncorhynchus mykiss at 1, 2, 3, 4, and 8 d after intracoelomic injection. No genotoxic damage was recorded, as no specimen showed a micronucleus number above the physiological range. Deltamethrin exposure elicited a transient reduction in the levels of superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase and a persistent decrease in glutathione reductase activity. Overall, the lower antioxidant enzyme activity in the deltamethrin-treated fish was mainly dose-dependent. Received May 27, 2016 accepted June 18, 2017.
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