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  • Title: Actions of deltamethrin and tralomethrin on cholinergic synaptic transmission in the central nervous system of the cockroach (Periplaneta americana).
    Author: Hue B, Mony L.
    Journal: Comp Biochem Physiol C Comp Pharmacol Toxicol; 1987; 86(2):349-52. PubMed ID: 2882930.
    Abstract:
    Deltamethrin (RU 22974) and tralomethrin isomers (RU 24784 and RU 24785) block transmission at the cercal-afferent giant-interneuron synapses of the cockroach, when bath-applied to the desheathed ganglion at micromolar concentrations. The time-course of the events leading to the blockage suggests two possible target sites: one located presynaptically and the other situated on postsynaptic membranes.
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