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  • Title: Antipsychotic drugs: prediction of side-effect profiles based on neuroreceptor data derived from human brain tissue.
    Author: Black JL, Richelson E.
    Journal: Mayo Clin Proc; 1987 May; 62(5):369-72. PubMed ID: 2883343.
    Abstract:
    The affinities of antipsychotic agents for neurotransmitter receptors are believed to be responsible for their antipsychotic activity and side-effect profiles. Data on neuroreceptor affinity can be used to predict side-effect profiles of antipsychotic drugs. In this report, we present data on receptor affinity that have been modified to help clinicians clearly see the potential for each drug to produce a specific side effect at any dosage.
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