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  • Title: Synthesis of some monosaccharide-related ester derivatives as insecticidal and acaricidal agents.
    Author: Huang X, Zhang B, Xu H.
    Journal: Bioorg Med Chem Lett; 2017 Sep 15; 27(18):4336-4340. PubMed ID: 28844385.
    Abstract:
    To develop natural-product-based pesticidal agents, a series of monosaccharide-related ester derivatives (17a-q and 18a-f), glucose (xylose)-piperic acid/piperic acid-like conjugates, were synthesized. Three-dimensional structures of compounds 17b, 17g, 17h, and 17n were unambiguously determined by single-crystal X-ray diffraction. Especially compounds 18e and 18f exhibited the most potent insecticidal and acaricidal activities against Mythimna separata and Tetranychus cinnabarinus. Their structure-activity relationships were also discussed.
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