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  • Title: Validation of Bioelectric Impedance Analysis against Dual-energy X-Ray Absorptiometry for Assessment of Body Composition in Indian Children Aged 5 to 18 Years.
    Author: Chiplonkar S, Kajale N, Ekbote V, Mandlik R, Parthasarathy L, Khadilkar V, Khadilkar A.
    Journal: Indian Pediatr; 2017 Nov 15; 54(11):919-924. PubMed ID: 28849765.
    Abstract:
    OBJECTIVE: To validate body composition measurements by Bioelectric Impedance Analysis (BIA) against Dual-Energy X-ray Absorptiometry (DXA) as the reference method in healthy children and adolescents. DESIGN: Cross-sectional. SETTING: Schools in and around Pune city, India. PARTICIPANTS: A random sample of 210 (114 boys, 96 girls) apparently healthy Indian children and adolescents (5-18 y). METHODS: Weight, height, Tanner stage (TS) were recorded. Body composition measures: fat-free mass (FFM), fat mass (FM), lean mass (LM), bone mineral content (BMC) and body fat percentage (%BF) were assessed by BIA and DXA on a single day. Agreement between the methods was estimated by Pearson's correlation, and Bland and Altman analysis. MAIN OUTCOME MEASURES: %BF, FM, FFM, LM, BMC. RESULTS: BIA underestimated %BF by 6.7 (3.7)% as compared to DXA. Mean FFM, BMC and LM by BIA were significantly higher than by DXA (P<0.001). These differences remained similar after adjusting for age, BMI and TS. Mean differences between FFM (-2.32 (1.39) kg), BMC (-0.18 (0.15) kg), and LM (-2.15 (1.34) kg) by DXA and BIA were significant (P<0.01). Correlations between BIA and DXA were 0.92 for %BF, 0.96 for LM and 0.98 for FFM and BMC. Both the methods were similar in identifying normal and overfat children as per their respective cut-offs. CONCLUSION: BIA and DXA techniques are not interchangeable for assessment of body composition. However, BIA may be used in the field/clinical setting preferably with ethnicity specific references.
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