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  • Title: [Regulation by catecholamines and cAMP of enzymes of thiol and disulfide metabolism].
    Author: Kolesnichenko LS, Mantorova NS, Shapiro LA.
    Journal: Biokhimiia; 1987 May; 52(5):743-9. PubMed ID: 2885035.
    Abstract:
    In vivo exo- and endogenous catecholamines have no influence on the activities of thioredoxin reductase, glutathione reductase, thiol transferase and nonselenium-dependent glutathione peroxidase. At the same time catecholamines activate via beta-adrenoceptors glutathione S-transferase and selenium-dependent glutathione peroxidase from many tissues and inhibit gamma-glutamyl transferase from kidney. In vitro cAMP has identical effects on the activities of the above enzymes. The possible significance of regulation of glutathione metabolism enzymes is discussed.
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