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Title: [The single nerve ending of the frog sartorius muscle: its ultrastructural characteristics and mediator secretion]. Author: Bezgina EN, Kashapova LA, Moshkov DA, Zefirov AL. Journal: Biull Eksp Biol Med; 1987 May; 103(5):617-21. PubMed ID: 2885046. Abstract: Electron microscopy and extracellular recordings were used for the investigation of structural and functional peculiarities of single frog sartorius muscle nerve terminal. It has been found that the diameter, length of the synaptic contact and quantity of synaptic vesicles decreased from proximal to distal parts of the nerve terminal. A number of varicosities, separated from each other by schwann cells, have been revealed along the course of the nerve terminal. This indicates the existence of an interrupted synaptic contact. Both the evoked and spontaneous transmitter release decreased from the initial to the end parts of the nerve terminal. The data obtained suggest that there is a correlation between structural heterogeneity and the differences in the transmitter release.[Abstract] [Full Text] [Related] [New Search]