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  • Title: Liposome encapsulated subunit (VP1) and virion vaccines against foot-and-mouth disease.
    Author: Vasantha S, Antony A, Lal SM.
    Journal: Acta Virol; 1987 Mar; 31(2):109-15. PubMed ID: 2886019.
    Abstract:
    Subunit vaccine prepared from VP1 protein of foot-and-mouth disease virus (FMDV) types 0 and Asia 1 protected guinea pigs against FMD and also induced high levels of antibody. Liposomes have been used as a safe and potent immunological adjuvant for FMD vaccines. Vaccines prepared from inactivated virus types 0 and Asia 1 encapsulated in liposomes protected guinea pigs against challenge with homologous virus and showed good antibody response in pigs on a small scale field trial.
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