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Title: Bottlenose dolphin (Tursiops truncatus) auditory brainstem responses recorded using conventional and randomized stimulation and averaging. Author: Finneran JJ. Journal: J Acoust Soc Am; 2017 Aug; 142(2):1034. PubMed ID: 28863595. Abstract: Auditory brainstem response (ABR) measurements using conventional averaging (i.e., constant interstimulus interval, ISI) are limited to stimulus rates low enough to prevent overlapping of the ABRs to successive stimuli. To overcome this limitation, stimuli may be presented at high rates using pseudorandom sequences (e.g., maximum length sequences) or quasi-periodic sequences; however, these methods restrict the available stimulus sequences and require deconvolution to recover the ABR from the overlapping responses. Randomized stimulation and averaging (RSA) is an alternate method where evoked responses at high rates are obtained by averaging responses to stimuli with ISIs drawn from a random distribution. The RSA method enables precise control over stimulus jitter, is flexible with respect to stimulus sequence parameters, and does not require deconvolution to extract the ABR waveform. In this study, ABRs were measured in three normal-hearing dolphins using conventional averaging and RSA. Results show the RSA method to be effective in dolphins if the ISI jitter ≥ ∼1.5 ms and that the influence of stimulus artifacts in the averaged ABR can be substantially reduced by alternating stimulus polarity on successive presentations rather than employing digital blanking or iterative processes.[Abstract] [Full Text] [Related] [New Search]