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  • Title: Effect of feeding pattern on the sensitivity of hepatic carnitine palmitoyl-transferase to inhibition by malonyl-CoA in the rat.
    Author: Escrivá F, Pascual-Leone AM, Hernández J, Ferré P, Girard J.
    Journal: Comp Biochem Physiol A Comp Physiol; 1987; 87(4):1041-3. PubMed ID: 2887369.
    Abstract:
    1. The feeding pattern influences the inhibitory effects of malonyl-CoA on carnitine palmitoyltransferase-I. 2. The sensitivity of liver carnitine palmitoyltransferase-I to malonyl-CoA is increased in rats meal-fed when compared to rats fed ad libitum. 3. Moreover, liver carnitine palmitoyltransferase-I of meal-fed rats remains more sensitive to inhibition by malonyl-CoA during a 24 hour fast than liver carnitine palmitoyltransferase-I of rats previously fed ad libitum.
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