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  • Title: Pyrogens fail to produce fever in the snakes Psammophis phillipsii and Lamprophis fuliginosus.
    Author: Zurovsky Y, Brain T, Laburn H, Mitchell D.
    Journal: Comp Biochem Physiol A Comp Physiol; 1987; 87(4):911-4. PubMed ID: 2887389.
    Abstract:
    1. Preferred body temperature of five diurnal, Psammophis philipsii and three nocturnal, Lamprophis fuliginosus, snakes was measured in a thermal gradient chamber by indwelling colonic thermocouples, before and after injection of a variety of pyrogens. 2. The snakes achieved their preferred body temperature by moving up and down in the gradient chamber; it was about 33 degrees C for P. phillipsii and 25 degrees C for L. fuliginosus. 3. The snakes did not develop fever in response to any of the pyrogens, whether gram-negative or gram-positive in origin, either on the day of injection or on the subsequent day. 4. We believe that fever is rare amongst reptiles.
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