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  • Title: [Lipoprotein metabolism and beta receptor blockers].
    Author: Schauer UJ, Schauer I.
    Journal: Z Gesamte Inn Med; 1987 Apr 15; 42(8):201-5. PubMed ID: 2888241.
    Abstract:
    Including own results a survey is given of the side effects of beta-receptor blockers on the plasma lipoprotein metabolism. The formation of a from the coronary-preventive point of view unfavourable lipoprotein risk profile under influence of individual beta-receptor blockers, among others propranolol, seems to be connected with an inhibition of a key enzyme in the lipoprotein metabolism, the lecithin-cholesterol-acyl transferase. Talinolol does not show these side effects. It is recommended to control the triglyceride level and the HDL cholesterol before the induction and after the beginning of a therapy with beta-receptor blockers and to use talinolol instead of propranolol in pre-existing dyslipoproteinaemia or in unfavourable changes during the treatment.
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