These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Triazole Resistance Is Still Not Emerging in Aspergillus fumigatus Isolates Causing Invasive Aspergillosis in Brazilian Patients.
    Author: Negri CE, Gonçalves SS, Sousa ACP, Bergamasco MD, Martino MDV, Queiroz-Telles F, Aquino VR, Castro PTO, Hagen F, Meis JF, Colombo AL.
    Journal: Antimicrob Agents Chemother; 2017 Nov; 61(11):. PubMed ID: 28893772.
    Abstract:
    Aspergillus fumigatus azole resistance has emerged as a global health problem. We evaluated the in vitro antifungal susceptibility of 221 clinical A. fumigatus isolates according to CLSI guidelines. Sixty-one isolates exhibiting MICs at the epidemiological cutoff value (ECV) for itraconazole or above the ECV for any triazole were checked for CYP51A mutations. No mutations were documented, even for the isolates (1.8%) with high voriconazole MICs, indicating that triazoles may be used safely to treat aspergillosis in Brazil.
    [Abstract] [Full Text] [Related] [New Search]