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Title: [Pregnancy intention and pregnancy-related anxiety in the second and third trimester: a birth cohort study].
Author: You Y, Yan SQ, Huang K, Mao LJ, Zhou SS, Ge X, Hao JH, Zhu P, Tao FB.
Journal: Zhonghua Liu Xing Bing Xue Za Zhi; 2017 Sep 10; 38(9):1179-1182. PubMed ID: 28910927.
Abstract:
Objective: To understand the association between pregnancy intention and pregnancy-related anxiety in the second and third trimester and its strength. Methods: A prospective cohort study was conducted in Ma'anshan, Anhui province. A total of 3 474 eligible pregnant women within 14 weeks of gestation were recruited. The information about their demographic characteristics were collected in early pregnancy. The completed questionnaire of pregnancy-related anxiety were asked to return in the second and third trimester. Logistic regression analysis was conducted to evaluate the association between pregnancy intention and pregnancy-related anxiety in the second and third trimester. Results: A total of 3 083 pregnant women were included in final analysis, The rate of unintentional pregnancy was 15.00% (n=461). The detection rates of pregnancy-related anxiety in the second and third trimester were 29.13% (n=898) and 30.36% (n=936). After controlling potential confounding factors, unintentional pregnancy increased the risk of pregnancy-related anxiety in the second trimester compared with intentional pregnancy (OR=1.85, 95%CI: 1.44-2.38); The risk of pregnancy-related anxiety also increased in the third trimester (OR=1.84, 95%CI: 1.44-2.35). Intentional pregnancy did not increase the risk of pregnancy-related anxiety in the second and third trimester. Conclusion: The study results suggests that unintentional pregnancy could increase the risk of pregnancy-related anxiety in the second and third trimester. 目的： 探讨妊娠意愿与孕中、晚期妊娠相关焦虑关联及其强度。 方法： 在马鞍山优生优育队列（MABC）中，将孕周≤14周、符合纳入标准的3 474名孕妇纳入队列。在首次产检时收集孕妇的一般人口学信息，并在孕中期和孕晚期收集妊娠相关焦虑量表。采用logistic回归分析妊娠意愿对孕中期和孕晚期妊娠相关焦虑的影响。 结果： 最终3 083人纳入分析，意外妊娠检出率为15.00%（n=461）。孕中期和孕晚期妊娠相关焦虑检出率分别为29.13%（n=898）、30.36% （n=936）。控制潜在的混杂因素后，与有充分思想准备的孕妇相比，意外妊娠的孕妇孕中期出现妊娠相关焦虑的风险增加（OR=1.85，95%CI：1.44~2.38）；孕晚期出现妊娠相关焦虑的风险也增加（OR=1.84，95%CI：1.44~2.35）；顺其自然怀孕的孕妇在孕中、晚期未增加妊娠相关焦虑发生风险。 结论： 意外妊娠是孕中、晚期妊娠相关焦虑危险因素。.

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