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  • Title: Nephrotic syndrome in infants and children: pathophysiology and management.
    Author: Downie ML, Gallibois C, Parekh RS, Noone DG.
    Journal: Paediatr Int Child Health; 2017 Nov; 37(4):248-258. PubMed ID: 28914167.
    Abstract:
    Nephrotic syndrome is defined by nephrotic-range proteinuria (≥40 mg/m2/hour or urine protein/creatinine ratio ≥200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (<25 g/L) and oedema. This review focuses on the classification, epidemiology, pathophysiology, management strategies and prognosis of idiopathic nephrotic syndrome of childhood, and includes a brief overview of the congenital forms.
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